The only time the Texans have won in this series was 2006, which was Gary Kubiak's first year as coach. The Texans upset the Colts 27-24 at Reliant Stadium. Now they're mired in a five-game losing streak.
In their last three games, the Texans have lost by four, six and three points.
"Any time you get beat it's frustrating, but we've got to find a way to finish a game," Kubiak said. "Whoever's got to make that play, whether it's a kick, a throw, a sack, an interception -- I mean, we've been in some great games, but good teams find a way to win those games."
The Texans are 5-5 and on the third leg of a four-game stretch against division opponents. In their last four losses, they've had the ball on the last series with a chance to win or force overtime, and they've blown them all.
The Colts are 10-0, one of two undefeated teams (along with New Orleans).
"Look at the Colts," Kubiak said. "They're a heck of a team. Look at the last four games they've won. They've been close games. They've won high-scoring games and low-scoring games. That's part of this business. You've got to find a way to win.
"We've been there, but we haven't made the play at the end to get it done."
The Colts have outscored the Texans 30.4 to 18.5 overall and 27.5 to 18.4 at Reliant Stadium. Before Kubiak arrived, the Texans scored more than 20 points against Indianapolis one time. Since Kubiak was hired, they've scored more than 20 points in five of seven games.
The Texans are coming off a short week after the 20-17 loss to the Titans on Monday night. They're playing the Colts for the second time in three games.
"I think it helps that they're a divisional opponent that we know well and that we only played them (three) weeks ago," quarterback Matt Schaub said. "It's imperative that we bounce back. Anytime you stumble in this business you got to turn around and bounce back next week.
"You have a rough play, or you make a mistake, you've got to bounce back the next play. It's imperative that we bounce back and get a W."